Good ideas, but I'd prefer to keep this setup in the training lobby. I like the challenge of staying within the confines of certain roles, yet making the setups interesting. Also, training players seem to take it a bit more seriously. Otherwise, great ideas, and when i make a sandbox version, I'll refer back to this.

I like your deck, Asylum, so I had a few ideas if you want...

You could lose one Jailer for a Nurse.
If you want, you could lose GS for Sherrif. It would stabilize the killing chaos but might make things boring with an always "clear" guy to claim to.
You could lose the hooker for a quack, this would be great for the theme, but then there'd be so many doctors it might be stupid...plus, the hooker is just such a good role for this setup gameplay-wise.
You could lose the spy for a poisoner, this fits the theme and could really shake things up with docs scrambling to cover all the deaths. Might make things a bit too chaotic, you might have to buff up the town or maybe add another nurse/doc.

Either way, just a couple little ideas, hope you like 'em :)